Here is a little tid-bit for you to think about. A friend is useing a 221 F.B with 50 gr. ballistic tips. The bullets are comeing out of barrel around 3000 F.P.S. So far a hand full of coyotes and 3-4 cats have been shot with this cal. Every coyote and cat had a splash entrance hole. Now another friend is useing a 243 with 58 gr. V-max and he was getting very little fur damage with his loads so i chrono'ed them to see how fast they came out. The load was suppose to be comeing out around 3650-3700, but the chrono showed only 3500 and this was with 25 degree temps. So in one cal. the low vel. bullet was badd where in the 243 the lower vel. was actually better for the hides. On another note i was shooting fox with my fire form loads which are putting out 36-3700 fps in my 17 pred. with 25 degree temps and a 30 gr. bullet. Fur damage was very little to none on the fox. And i do know from exsperiance a 17 rem with 25 gr. bullets going 4000 can tear up the fox.